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KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)

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Trial Profile

KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Apr 2025

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At a glance

  • Drugs Pembrolizumab (Primary) ; Antineoplastics
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms KEYNOTE-U01; MK-3475-U01/KEYNOTE-U01; umbrella master protocol
  • Sponsors Merck Sharp & Dohme Corp.

Most Recent Events

  • 18 Nov 2024 Planned number of patients changed from 825 to 1065.
  • 18 Oct 2024 Planned number of patients changed from 735 to 825.
  • 23 Apr 2024 Planned number of patients changed from 260 to 735.

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