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Phase II study of nivolumab + abemaciclib + endocrine therapy in patients with HR-positive HER2-negative metastatic breast cancer Nivolumab Evaluation With endocrine therapy (Fulvestrant or Letrozole) and AbeMaciclib (NEWFLAME) study (WJOG11418B Investigator-Initiated Clinical Trial)

Trial Profile

Phase II study of nivolumab + abemaciclib + endocrine therapy in patients with HR-positive HER2-negative metastatic breast cancer Nivolumab Evaluation With endocrine therapy (Fulvestrant or Letrozole) and AbeMaciclib (NEWFLAME) study (WJOG11418B Investigator-Initiated Clinical Trial)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 14 Dec 2021

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At a glance

  • Drugs Abemaciclib (Primary) ; Nivolumab (Primary) ; Fulvestrant; Letrozole
  • Indications Advanced breast cancer
  • Focus Therapeutic Use
  • Acronyms NEWFLAME

Most Recent Events

  • 17 Jan 2020 New trial record
  • 14 Dec 2019 Trial design presented at the 42nd Annual San Antonio Breast Cancer Symposium

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