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A pilot study of Neoadjuvant weekly paclitaxel (wP) and carboplatin (Cb) with trastuzumab (T) and pertuzumab (P) in HER2-positive breast cancer (H+BC )and to assess whether patients (pts) with a suboptimal response to this regimen benefit from switching to doxorubicin/cyclophosphamide (AC)

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A pilot study of Neoadjuvant weekly paclitaxel (wP) and carboplatin (Cb) with trastuzumab (T) and pertuzumab (P) in HER2-positive breast cancer (H+BC )and to assess whether patients (pts) with a suboptimal response to this regimen benefit from switching to doxorubicin/cyclophosphamide (AC)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Jan 2020

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At a glance

  • Drugs Carboplatin (Primary) ; Cyclophosphamide (Primary) ; Doxorubicin (Primary) ; Paclitaxel (Primary) ; Pertuzumab (Primary) ; Trastuzumab (Primary)
  • Indications Advanced breast cancer; Early breast cancer; HER2 positive breast cancer
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 17 Jan 2020 New trial record
    • 14 Dec 2019 Results assessing efficacy(pCR) and safety of wPCbTP and doxorubicin/cyclophosphamide presented at the 42nd Annual San Antonio Breast Cancer Symposium

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