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Phase II Trial of Reduced Intensity Conditioning Hematopoietic Stem Cell Transplantation for Primary Immune Deficiencies, Immune Dysregulatory Syndromes, and Inherited Bone Marrow Failure Syndromes Using Post-Transplant Cyclophosphamide

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Phase II Trial of Reduced Intensity Conditioning Hematopoietic Stem Cell Transplantation for Primary Immune Deficiencies, Immune Dysregulatory Syndromes, and Inherited Bone Marrow Failure Syndromes Using Post-Transplant Cyclophosphamide

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 10 Dec 2024

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At a glance

  • Drugs Alemtuzumab (Primary) ; Cyclophosphamide (Primary) ; Fludarabine (Primary) ; Melphalan (Primary) ; Mycophenolate mofetil (Primary) ; Tacrolimus (Primary) ; Tacrolimus (Primary)
  • Indications Graft-versus-host disease
  • Focus Therapeutic Use

    • Most Recent Events

    • 06 Dec 2024 Planned End Date changed from 31 Dec 2026 to 31 Dec 2028.
    • 06 Dec 2024 Planned primary completion date changed from 31 Dec 2024 to 31 Dec 2027.
    • 23 Jan 2020 New trial record

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