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ESCALATE, A Phase III Randomized Study Comparing Enzalutamide or Darolutamide With Radium-223 vs Enzalutamide or Darolutamide With Placebo and the Effect Upon Symptomatic Skeletal Event-Free Survival for mCRPC Patients

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Trial Profile

ESCALATE, A Phase III Randomized Study Comparing Enzalutamide or Darolutamide With Radium-223 vs Enzalutamide or Darolutamide With Placebo and the Effect Upon Symptomatic Skeletal Event-Free Survival for mCRPC Patients

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 10 Oct 2022

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At a glance

  • Drugs Radium 223 chloride (Primary) ; Darolutamide; Enzalutamide
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Therapeutic Use
  • Acronyms ESCALATE

Most Recent Events

  • 22 Jul 2022 The number of treatment arms increased from 2 to 6. Time frame of primary endpoint amended.
  • 30 Mar 2022 Status changed from active, no longer recruiting to discontinued.
  • 30 Jun 2021 Status changed from recruiting to active, no longer recruiting.

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