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Effects of Sodium Glucose Co-Transporter 2 Inhibitor Therapy on Pancreatic and hepatic fat content using 3.0 Tesla Magnetic Resonance Imaging Proton Density Fat Fraction Software in patients of Type 2 Diabetes Mellitus when treated according to current guidelines Protocol: Prospective Open Label Case Control 16 weeks Proof of Concept Study.

Trial Profile

Effects of Sodium Glucose Co-Transporter 2 Inhibitor Therapy on Pancreatic and hepatic fat content using 3.0 Tesla Magnetic Resonance Imaging Proton Density Fat Fraction Software in patients of Type 2 Diabetes Mellitus when treated according to current guidelines Protocol: Prospective Open Label Case Control 16 weeks Proof of Concept Study.

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 15 Mar 2022

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At a glance

  • Drugs Dapagliflozin (Primary)
  • Indications Obesity; Type 2 diabetes mellitus
  • Focus Proof of concept; Therapeutic Use
  • Sponsors AstraZeneca India

Most Recent Events

  • 09 Mar 2022 Primary endpoint has been met. (Participants who have completed 120 day intervention with SGLT 2 inhibitor therapy will be evaluated for decrease in pancreatic and hepatic fat percentage, through MRI (3.0 Tesla). We hypothesise the usage of SGLT2 inhibitor will decrease 5% of liver and 1% of pancreatic fat content)
  • 09 Mar 2022 Status changed to completed.
  • 09 Mar 2022 Results published in the Journal of Clinical Endocrinology and Metabolism.

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