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A Phase I, Open-label Multi-dose Pharmacokinetic and Safety Study of Oral Tazemetostat in Subjects With Moderate and Severe Hepatic Impairment With Advanced Malignancies

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Trial Profile

A Phase I, Open-label Multi-dose Pharmacokinetic and Safety Study of Oral Tazemetostat in Subjects With Moderate and Severe Hepatic Impairment With Advanced Malignancies

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 25 Jun 2025

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At a glance

  • Drugs Tazemetostat (Primary)
  • Indications Haematological malignancies; Solid tumours
  • Focus Pharmacokinetics
  • Sponsors Epizyme

Most Recent Events

  • 19 Jun 2025 Planned End Date changed from 17 Jun 2025 to 31 Dec 2025.
  • 19 Jun 2025 Planned primary completion date changed from 20 May 2025 to 30 Sep 2025.
  • 31 Jan 2025 Planned End Date changed from 28 Jun 2025 to 17 Jun 2025.

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