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Clinical study for efficacy and safety of Oncorine (Recombinant Human Adenovirus Type 5 Injection) combined with mFOLFOX6+ bevacizumab in the treatment of unresectable colorectal adenocarcinoma with liver metastases

Trial Profile

Clinical study for efficacy and safety of Oncorine (Recombinant Human Adenovirus Type 5 Injection) combined with mFOLFOX6+ bevacizumab in the treatment of unresectable colorectal adenocarcinoma with liver metastases

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 03 Jul 2024

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At a glance

  • Drugs H-101 (Primary) ; Bevacizumab; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Colorectal cancer; Gastric cancer; Liver metastases
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TROJAN 021

Most Recent Events

  • 04 Jun 2024 Results (n=21) assessing safety and efficacy of recombinant human adenovirus type 5 (H101) combined with immune checkpoint inhibitors (ICIs) in patients with liver metastatic gastric cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology
  • 08 Jun 2021 Results (n=8) assessing safety and efficacy of H101 treatment in patients with hepatic metastasis of colorectal cancer, presented at the 57th Annual Meeting of the American Society of Clinical Oncology.
  • 03 Feb 2020 New trial record

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