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Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery, Compared With Fresh Frozen Plasma: Study Protocol for a Non-inferiority, Randomized Controlled Trial

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Trial Profile

Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery, Compared With Fresh Frozen Plasma: Study Protocol for a Non-inferiority, Randomized Controlled Trial

Status: Discontinued
Phase of Trial: Phase IV

Latest Information Update: 30 Jun 2026

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At a glance

Most Recent Events

  • 24 Jun 2026 Actual primary completion date changed from 10 Mar 2025 to 11 Mar 2025.
  • 24 Jun 2026 Status changed from recruiting to discontinued. (At a meeting on February 17, 2025, the Data and Safety Monitoring Board recommended early termination because the predefined efficacy boundary was crossed.)
  • 26 Oct 2024 Status changed from not yet recruiting to recruiting.

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