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A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of QM1114-DP for the Treatment of Moderate to Severe Lateral Canthal Lines

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Trial Profile

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of QM1114-DP for the Treatment of Moderate to Severe Lateral Canthal Lines

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 31 Jul 2026

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At a glance

  • Drugs Botulinum Toxin A (Primary)
  • Indications Facial wrinkles
  • Focus Registrational; Therapeutic Use
  • Acronyms READY-2
  • Sponsors Galderma Research & Development

Most Recent Events

  • 01 Jul 2026 According to Galderma Media Release, Galderma received a recent Complete Response Letter (CRL) from the U.S. Food & Drug Administration (FDA) addressing remaining observations on the manufacturing site and analytical method optimization. Galderma is fully committed to resolving these topics promptly and to continue working constructively with the FDA; advancing RelabotulinumtoxinA in the U.S. remains a top priority.
  • 02 Feb 2026 According to Galderma Media Release, the company announced that the U.S. FDA has accepted the BLA resubmission for RelabotulinumtoxinA for the temporary improvement of moderate-to-severe glabellar lines (frown lines) and lateral canthal lines (crows feet) in adults.
  • 01 Mar 2025 Results assessing Efficacy and Safety of RelabotulinumtoxinA Liquid Botulinum Toxin in the Treatment of Lateral Canthal Lines published in the Dermatologic Surgery

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