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A Phase Ia/Ib, Open-Label, Multicenter, Global, Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of XmAb24306 as a Single Agent and in Combination With Atezolizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Trial Profile

A Phase Ia/Ib, Open-Label, Multicenter, Global, Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of XmAb24306 as a Single Agent and in Combination With Atezolizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 06 Jun 2025

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At a glance

Most Recent Events

  • 31 May 2025 Planned End Date changed from 14 Sep 2025 to 15 Dec 2025.
  • 31 May 2025 Planned primary completion date changed from 14 Sep 2025 to 15 Dec 2025.
  • 30 Apr 2025 Results(n=91) assessing safety, tolerability, pharmacokinetics (PK), PD, and activity of EBA in combination with atezolizumab (ATZ) in Phase 1a (Ph 1a) and Ph 1b, presented at the 116th Annual Meeting of the American Association for Cancer Research.

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