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A Phase 1 Study to Evaluate the Effect of Multiple IV Infusions of Risankizumab on the Pharmacokinetics of Cytochrome P450 Substrates Administered Orally in Subjects With Moderately to Severely Active Ulcerative Colitis or Crohn's Disease

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Trial Profile

A Phase 1 Study to Evaluate the Effect of Multiple IV Infusions of Risankizumab on the Pharmacokinetics of Cytochrome P450 Substrates Administered Orally in Subjects With Moderately to Severely Active Ulcerative Colitis or Crohn's Disease

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 15 Jul 2024

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At a glance

  • Drugs Risankizumab (Primary) ; Caffeine; Metoprolol; Midazolam; Omeprazole; Vitamin K; Warfarin
  • Indications Crohn's disease; Ulcerative colitis
  • Focus Pharmacokinetics
  • Sponsors AbbVie

    • Most Recent Events

    • 20 Oct 2022 Status changed from active, no longer recruiting to completed.
    • 02 Jun 2022 Planned primary completion date changed from 6 Jan 2023 to 3 Mar 2023.
    • 02 Jun 2022 Status changed from recruiting to active, no longer recruiting.

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