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The Effect of Tirzepatide Versus Dulaglutide on Major Adverse Cardiovascular Events in Patients With Type 2 Diabetes (SURPASS-CVOT)

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Trial Profile

The Effect of Tirzepatide Versus Dulaglutide on Major Adverse Cardiovascular Events in Patients With Type 2 Diabetes (SURPASS-CVOT)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 Aug 2025

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At a glance

  • Drugs Tirzepatide (Primary) ; Dulaglutide
  • Indications Cardiovascular disorders; Type 2 diabetes mellitus
  • Focus Registrational; Therapeutic Use
  • Acronyms SURPASS-CVOT
  • Sponsors Eli Lilly and Company

Most Recent Events

  • 31 Jul 2025 According to Eli Lilly and Company media release, detailed results for SURPASS-CVOT will be presented at the European Association for the Study of Diabetes (EASD) Annual Meeting 2025 in September and published in a peer-reviewed journal. Company plans to submit these data to global regulatory authorities by the end of this year.
  • 31 Jul 2025 Primary endpoint has been met (Time to First Occurrence of Death from Cardiovascular (CV) Causes, Myocardial Infarction (MI), or Stroke (MACE-3)) , according to Eli Lilly and Company media release
  • 31 Jul 2025 According to Eli Lilly and Company media release, company announced topline results from SURPASS-CVOT, in adults with type 2 diabetes and established atherosclerotic cardiovascular disease.

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