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A study to investigate the effects of TAS‐303 on CYP3A activity in the small intestine and liver in healthy participants by evaluating the pharmacokinetics (PK) of single‐dose oral simvastatin or intravenous midazolam, after repeated oral administration of TAS‐303

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Trial Profile

A study to investigate the effects of TAS‐303 on CYP3A activity in the small intestine and liver in healthy participants by evaluating the pharmacokinetics (PK) of single‐dose oral simvastatin or intravenous midazolam, after repeated oral administration of TAS‐303

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 13 Feb 2020

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At a glance

  • Drugs TAS 303 (Primary) ; Midazolam; Simvastatin
  • Indications Urinary-Stress-Incontinence
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Taiho Pharmaceutical

    • Most Recent Events

    • 13 Feb 2020 New trial record
    • 05 Feb 2020 Results published in the Journal of Clinical Pharmacology

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