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Thoracic Radiotherapy plus Durvalumab in Elderly and/or frail NSCLC stage III patients unfit for chemotherapy- Employing optimized (hypofractionated) radiotherapy to foster durvalumab efficacy

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Trial Profile

Thoracic Radiotherapy plus Durvalumab in Elderly and/or frail NSCLC stage III patients unfit for chemotherapy- Employing optimized (hypofractionated) radiotherapy to foster durvalumab efficacy

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 06 Jan 2026

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At a glance

  • Drugs Durvalumab (Primary)
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TRADE-hypo

Most Recent Events

  • 05 Dec 2025 Planned primary completion date changed from 31 Oct 2025 to 28 Feb 2026.
  • 01 May 2025 Status changed from recruiting to active, no longer recruiting.
  • 24 Oct 2023 Interim results (n=38) from TRADE hypo study presented at the 48th European Society for Medical Oncology Congress

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