A Phase Ib /II Open-label, Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of APG-2575 Single Agent or in Combination With Ibrutinib or Rituximab in Patients With Waldenstrom Macroglobulinemia (MAPLE-1)
Latest Information Update: 21 Aug 2024
At a glance
- Drugs Ibrutinib (Primary) ; Lisaftoclax (Primary) ; Rituximab (Primary)
- Indications Waldenstrom's macroglobulinaemia
- Focus Adverse reactions
- Acronyms MAPLE-1
- Sponsors Ascentage Pharma
Most Recent Events
- 19 Aug 2024 Status changed from recruiting to completed.
- 04 Jun 2024 Updated efficacy and safety results (as of January 25, 2024, n=46 pts) presented at the 60th Annual Meeting of the American Society of Clinical Oncology
- 01 Jun 2024 According to an Ascentage Pharma media release, data from this study presented at the 60th American Society of Clinical Oncology (ASCO) Annual Meeting