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A Global Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of the Half-life Extended Bispecific T-cell Engager AMG 910 in Subjects With Claudin 18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma

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Trial Profile

A Global Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of the Half-life Extended Bispecific T-cell Engager AMG 910 in Subjects With Claudin 18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 31 Jan 2024

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At a glance

  • Drugs AMG 910 (Primary)
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Adverse reactions; First in man
  • Sponsors Amgen

    • Most Recent Events

    • 03 Jun 2022 Status changed from active, no longer recruiting to completed.
    • 08 Dec 2021 Planned End Date changed from 15 Oct 2025 to 1 Nov 2023.
    • 08 Dec 2021 Planned primary completion date changed from 15 Oct 2025 to 1 Nov 2023.

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