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A Randomized, Open-label, Controlled, Phase 2 Study of Pevonedistat, Venetoclax, and Azacitidine Versus Venetoclax Plus Azacitidine in Adults With Newly Diagnosed Acute Myeloid Leukemia Who Are Unfit for Intensive Chemotherapy

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A Randomized, Open-label, Controlled, Phase 2 Study of Pevonedistat, Venetoclax, and Azacitidine Versus Venetoclax Plus Azacitidine in Adults With Newly Diagnosed Acute Myeloid Leukemia Who Are Unfit for Intensive Chemotherapy

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Dec 2024

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At a glance

  • Drugs Pevonedistat (Primary) ; Azacitidine; Azacitidine; Venetoclax
  • Indications Acute myeloid leukaemia
  • Focus Therapeutic Use
  • Acronyms PEVENAZA
  • Sponsors Takeda; Takeda Oncology

    • Most Recent Events

    • 17 Dec 2024 Planned End Date changed from 31 Dec 2024 to 31 Mar 2025.
    • 31 Oct 2024 Planned End Date changed from 30 Sep 2024 to 31 Dec 2024.
    • 28 Aug 2024 Planned End Date changed from 30 Jun 2024 to 30 Sep 2024.

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