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Phase 1b/2a, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study of Safety, Tolerability, and Efficacy of Intravenous AP-SA02 as an Adjunct to Best Available Antibiotic Therapy for the Treatment of Adults With Bacteremia Due to Staphylococcus Aureus

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Trial Profile

Phase 1b/2a, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study of Safety, Tolerability, and Efficacy of Intravenous AP-SA02 as an Adjunct to Best Available Antibiotic Therapy for the Treatment of Adults With Bacteremia Due to Staphylococcus Aureus

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 27 May 2025

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At a glance

  • Drugs AP-SA02 (Primary) ; Antibacterials
  • Indications Bacteraemia; Staphylococcal infections
  • Focus Adverse reactions; First in man
  • Acronyms diSArm Study
  • Sponsors Armata Pharmaceuticals

Most Recent Events

  • 19 May 2025 Positive topline results from this trial has been presented in the Armata Pharmaceuticals media release.
  • 01 May 2025 According to an Armata Pharmaceuticals media release, topline data anticipated in Q2 2025 to support potential future pivotal bacteremia efficacy trial
  • 01 May 2025 According to an Armata Pharmaceuticals media release, company Received 4.65 Million of Additional Non-Dilutive Award Funding from the U.S. Department of Defense to Support diSArm Clinical Trial of AP-SA02. The amount will be used to support Phase 2a study close out activities as well as for the preparation and execution of an end-of-phase 2 meeting with the U.S. Food and Drug Administration.

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