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Combined Prevention of Sexually Transmitted Infections (STIs) in Men Who Have Sex With Men and Using Oral Tenofovir Disoproxil Fumarate/ Emtricitabine (TDF/FTC) for HIV Pre-Exposure Prophylaxis (PrEP)

Trial Profile

Combined Prevention of Sexually Transmitted Infections (STIs) in Men Who Have Sex With Men and Using Oral Tenofovir Disoproxil Fumarate/ Emtricitabine (TDF/FTC) for HIV Pre-Exposure Prophylaxis (PrEP)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 21 Oct 2024

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At a glance

  • Drugs Meningococcal vaccine group B OMV Novartis (Primary) ; Doxycycline
  • Indications Bacterial infections; Chlamydial infections; Enterobacteriaceae infections; Gonorrhoea; Sexually transmitted infections; Staphylococcal infections; Syphilis
  • Focus Therapeutic Use
  • Acronyms DOXYVAC
  • Most Recent Events

    • 01 Oct 2024 Results assessing post-exposure prophylaxis (PEP) with doxycycline could reduce the incidence of chlamydia or syphilis (or both) and the meningococcal group B vaccine (4CMenB) could reduce the incidence of gonorrhoea in this study population, were published in The Lancet Infectious Diseases
    • 30 Jul 2024 Status changed from discontinued to completed.
    • 12 Mar 2024 Status has been changed to discontinued, as per results presented at the 31st Conference on Retroviruses and Opportunistic Infections 2024

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