Trial Profile

An Adaptive, Randomized, Placebo-controlled, Double-blind, Multi-center Study of Oral Etavopivat, a Pyruvate Kinase Activator in Patients With Sickle Cell Disease (HIBISCUS)

Status: Active, no longer recruiting

Phase of Trial: Phase II/III

Latest Information Update: 28 May 2025

Price :

$35 ^*

Note:

Adis is an information provider.
Final gross price and currency may vary according to local VAT and billing address.
Your purchase entitles you to full access to the information contained in our trial profile at the time of purchase.
A link to download a PDF version of the trial profile will be included in your email receipt.

At a glance

Drugs Etavopivat (Primary)
Indications Sickle cell anaemia
Focus Registrational; Therapeutic Use
Acronyms HIBISCUS; PRAISE
Sponsors FORMA Therapeutics; Novo Nordisk

Most Recent Events

11 Apr 2025 Planned End Date changed from 31 Mar 2027 to 19 Mar 2027.
11 Apr 2025 Planned primary completion date changed from 31 Mar 2026 to 20 Feb 2026.
11 Mar 2025 Status changed from recruiting to active, no longer recruiting.

You need to be a logged in or subscribed to view this content

If your organization or you do not have a subscription, try one of the following:

Contacting your organization’s admin about adding this content to your AdisInsight subscription
Buying a PDF version of any individual profile
Request a free trial (opens in a new window)

If your organization has a subscription, there are several access options, even while working remotely:

Working within your organization’s network
Login with username/password or try to access via your institution
Persisted access using your organization’s identifier stored in your user browser for 90 days

For assistance, contact us at asktheexpert.adisinsight@springer.com