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A Randomised Study of Interferon-free Treatment for Recently Acquired Hepatitis C in People Who Inject Drugs and People With HIV Coinfection.

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Trial Profile

A Randomised Study of Interferon-free Treatment for Recently Acquired Hepatitis C in People Who Inject Drugs and People With HIV Coinfection.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 21 Jul 2023

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At a glance

  • Drugs Sofosbuvir/velpatasvir (Primary)
  • Indications Hepatitis C
  • Focus Therapeutic Use
  • Acronyms REACT

    • Most Recent Events

    • 18 Jul 2023 Results assessing incidence of, and factors associated with reinfection among people treated for recent HCV , published in the AIDS
    • 20 May 2021 Primary endpoint (The proportion of participants with undetectable HCV RNA at 12 weeks post end of treatment following SOF/VEL for 6 weeks as compared with 12 weeks in people with recent HCV infection (duration of infection less than or equal to 12 months)) has not been met, according results published in the Journal of Hepatology.
    • 20 May 2021 Results assessing to compare the efficacy and safety of sofosbuvir/velpatasvir administered for 6 or 12 weeks in individuals with recent HCV infection, published in the Journal of Hepatology.

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