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Randomized, Phase III Study of Early Intervention With Venetoclax and Obinutuzumab Versus Delayed Therapy With Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): EVOLVE CLL/SLL Study

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Trial Profile

Randomized, Phase III Study of Early Intervention With Venetoclax and Obinutuzumab Versus Delayed Therapy With Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): EVOLVE CLL/SLL Study

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 19 Mar 2025

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At a glance

  • Drugs Obinutuzumab (Primary) ; Venetoclax (Primary)
  • Indications Chronic lymphocytic leukaemia
  • Focus Therapeutic Use
  • Acronyms EVOLVE CLL/SLL

    • Most Recent Events

    • 14 Dec 2021 At the time of submission of trial design, 7 patients have been registered and randomized per protocol as reported in 63rd American Society of Hematology Annual Meeting and Exposition
    • 14 Dec 2021 Trial design presented at the 63rd American Society of Hematology Annual Meeting and Exposition
    • 08 Jun 2021 Trial design presented at the 57th Annual Meeting of the American Society of Clinical Oncology.

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