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A Phase I, Open-label, Dose Escalation Clinical Trial to Assess the Safety, Efficacy, Tolerability and Pharmacokinetics of the Recombinant Humanized Anti-PD1 Monoclonal Antiody (JS001) in Combination With Recombinant Humanized Anti-HER2 Monoclonal Antibody-MMAE Conjugate (RC48-ADC) in Treatment of HER2-Positive Advanced Malignant Solid Tumors

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Trial Profile

A Phase I, Open-label, Dose Escalation Clinical Trial to Assess the Safety, Efficacy, Tolerability and Pharmacokinetics of the Recombinant Humanized Anti-PD1 Monoclonal Antiody (JS001) in Combination With Recombinant Humanized Anti-HER2 Monoclonal Antibody-MMAE Conjugate (RC48-ADC) in Treatment of HER2-Positive Advanced Malignant Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 07 Feb 2024

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At a glance

  • Drugs Disitamab vedotin (Primary) ; Toripalimab (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions

    • Most Recent Events

    • 02 Feb 2024 According to RemeGen media release, data from this study published in in The Lancet sub-journal eClinicalMedicine
    • 02 Feb 2024 Results published in the RemeGen Media Release
    • 23 Aug 2023 Planned End Date changed from 1 Dec 2021 to 1 Dec 2024.

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