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Interventional, Open-label, One-sequence Study to Investigate the Effects of Multiple Doses of Foliglurax on the Pharmacokinetics of Cytochrome P450 (CYP450) Substrates Caffeine (CYP1A2), Montelukast (CYP2C8), and Midazolam (CYP3A4) in Healthy Subjects

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Trial Profile

Interventional, Open-label, One-sequence Study to Investigate the Effects of Multiple Doses of Foliglurax on the Pharmacokinetics of Cytochrome P450 (CYP450) Substrates Caffeine (CYP1A2), Montelukast (CYP2C8), and Midazolam (CYP3A4) in Healthy Subjects

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs Foliglurax (Primary) ; Caffeine; Midazolam; Montelukast
  • Indications Parkinson's disease
  • Focus Pharmacokinetics
  • Sponsors Lundbeck A/S

Most Recent Events

  • 27 Mar 2020 According to Lundbeck A/S Media Release, the development programme of foliglurax is terminated as foliglurax did not demonstrate sufficient efficacy for patients living with Parkinson's disease
  • 27 Mar 2020 Status changed from recruiting to discontinued.
  • 25 Feb 2020 New trial record

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