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A Phase 3, Open-Label, Multicenter, Randomized, Active-controlled Study to Assess PK and Compare the Efficacy, Safety, and Tolerability of P1101 vs Anagrelide as 2nd Line Therapy for Essential Thrombocythemia (SURPASS ET): The Core Study and Its Extension Study

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Trial Profile

A Phase 3, Open-Label, Multicenter, Randomized, Active-controlled Study to Assess PK and Compare the Efficacy, Safety, and Tolerability of P1101 vs Anagrelide as 2nd Line Therapy for Essential Thrombocythemia (SURPASS ET): The Core Study and Its Extension Study

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 02 Sep 2025

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At a glance

  • Drugs Ropeginterferon alfa-2b (Primary) ; Anagrelide
  • Indications Essential thrombocythaemia
  • Focus Registrational; Therapeutic Use
  • Acronyms SURPASS ET
  • Sponsors PharmaEssentia Corporation

Most Recent Events

  • 13 Aug 2025 Planned End Date changed from 30 Dec 2025 to 31 Aug 2029.
  • 03 Jun 2025 According to a PharmaEssentia Corporation media release, data from the study will be presented at the 2025 European Hematology Association (EHA) Congress, taking place June 12-15 in Milan, Italy.
  • 20 May 2025 According to a PharmaEssentia Corporation media release, data from the study will be presented in an oral session at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place May 30-June 3 in Chicago.

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