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A Randomized Study to Investigate the Efficacy and Safety of the Tumor-targeting Human Antibody-cytokine Fusion Protein L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma

Trial Profile

A Randomized Study to Investigate the Efficacy and Safety of the Tumor-targeting Human Antibody-cytokine Fusion Protein L19TNF in Previously Treated Patients with Advanced Stage or Metastatic Soft-tissue Sarcoma

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 11 Feb 2025

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At a glance

  • Drugs Onfekafusp alfa (Primary) ; Dacarbazine
  • Indications Soft tissue sarcoma
  • Focus Therapeutic Use
  • Acronyms FLASH
  • Sponsors Philogen

Most Recent Events

  • 04 Feb 2025 According to a Philogen media release, study read out expected between April and July 2025, based on the occurrence of the events, If the trial reads-out positively, Philogen plans to request a pre-BLA meeting with FDA to discuss opportunities for accelerated approval procedures in the US
  • 27 Jan 2025 Planned End Date changed from 1 Dec 2024 to 1 Dec 2025.
  • 27 Jan 2025 Planned primary completion date changed from 1 Dec 2024 to 1 Dec 2025.

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