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Multicenter, Randomized, Placebo-controlled, Double-blind, Parallel Group, Dose-finding Phase 2 Study to Evaluate Efficacy and Safety of BAY2433334 in Patients Following an Acute Non-cardioembolic Ischemic Stroke

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Trial Profile

Multicenter, Randomized, Placebo-controlled, Double-blind, Parallel Group, Dose-finding Phase 2 Study to Evaluate Efficacy and Safety of BAY2433334 in Patients Following an Acute Non-cardioembolic Ischemic Stroke

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Feb 2024

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At a glance

  • Drugs Asundexian (Primary)
  • Indications Brain infarction; Stroke
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms PACIFIC-STROKE
  • Sponsors Bayer

    • Most Recent Events

    • 10 Feb 2023 Results (n=1440) of secondary analysis hypothesizing that asundexian would be more effective in patients enrolled with large, multiple or cortical acute infarcts on MRI than in patients enrolled with a single small subcortical acute infarct presented at the International Stroke Conference 2023
    • 10 Feb 2023 Results of post hoc analysis assessing Effects Of The Oral Factor XIa Inhibitor Asundexian On Intracranial Bleeding Among Patients With Acute Non-Cardioembolic Ischemic Stroke presented at the International Stroke Conference 2023
    • 08 Feb 2023 According to Bayer media release, data from this study will be presented at the International Stroke Conference, February 8-10 2023.

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