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A Phase 1, Multicenter, Open-label, Dose-Exploration and Dose-Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 650 in Subjects With Advanced Solid Tumors

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Trial Profile

A Phase 1, Multicenter, Open-label, Dose-Exploration and Dose-Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 650 in Subjects With Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 28 Aug 2023

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At a glance

  • Drugs Rovilnesib (Primary)
  • Indications Advanced breast cancer; Endometrial cancer; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer; Solid tumours; Triple negative breast cancer
  • Focus Adverse reactions
  • Sponsors Amgen; Volastra Therapeutics

Most Recent Events

  • 07 Mar 2023 Status changed from active, no longer recruiting to completed.
  • 26 Jan 2023 Planned End Date changed from 26 Mar 2024 to 27 Feb 2023.
  • 23 Aug 2022 Planned End Date changed from 24 Apr 2025 to 26 Mar 2024.

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