A Phase III, Randomized, Double-Blinded, Placebo-Controlled Study of Tiragolumab, an Anti-Tigit Antibody, in Combination With Atezolizumab Compared With Placebo in Combination With Atezolizumab in Patients With Previously Untreated Locally Advanced Unresectable or Metastatic PD-L1-Selected Non-Small Cell Lung Cancer
Latest Information Update: 12 Jun 2025
At a glance
- Drugs Atezolizumab (Primary) ; Tiragolumab (Primary)
- Indications Non-small cell lung cancer
- Focus Adverse reactions; Registrational; Therapeutic Use
- Acronyms SKYSCRAPER-01
- Sponsors Chugai Pharmaceutical; Roche
Most Recent Events
- 30 Apr 2025 Primary endpoint(Investigator-Assessed Progression-Free Survival (PFS) in the Primary Analysis Set) has not been met.
- 30 Apr 2025 Primary endpoint(Overall Survival (OS) in the Primary Analysis Set) has not been met.
- 30 Apr 2025 Results(n=534) evaluating efficacy and safety of tiragolumab plus atezolizumab compared with placebo plus atezolizumab presented at the 116th Annual Meeting of the American Association for Cancer Research.