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A Phase I Study of the Adam-10 Inhibitor, INCB7839 in Children With Recurrent/Progressive High-Grade Gliomas to Target Microenvironmental Neuroligin-3

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Trial Profile

A Phase I Study of the Adam-10 Inhibitor, INCB7839 in Children With Recurrent/Progressive High-Grade Gliomas to Target Microenvironmental Neuroligin-3

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 26 Feb 2025

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At a glance

  • Drugs Aderbasib (Primary)
  • Indications Anaplastic astrocytoma; Diffuse intrinsic pontine glioma; Glioblastoma; Glioma; Oligodendroglioma
  • Focus Adverse reactions; Pharmacokinetics

    • Most Recent Events

    • 19 Feb 2025 Status changed from active, no longer recruiting to completed.
    • 15 Nov 2024 Planned End Date changed from 30 Jun 2024 to 31 Mar 2025.
    • 11 May 2023 Status changed from recruiting to active, no longer recruiting.

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