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A multi-stage randomised trial of durvalumab (Medi4736) with chemoradiotherapy with 5-fluorouracil and mitomycin C in patients with muscle-invasive bladder cancer

Trial Profile

A multi-stage randomised trial of durvalumab (Medi4736) with chemoradiotherapy with 5-fluorouracil and mitomycin C in patients with muscle-invasive bladder cancer

Status: Recruiting
Phase of Trial: Phase II/III

Latest Information Update: 25 Jun 2026

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At a glance

  • Drugs Durvalumab (Primary) ; Fluorouracil; Mitomycin
  • Indications Adenocarcinoma; Bladder cancer; Carcinoma; Squamous cell cancer; Transitional cell carcinoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms Rad-IO

Most Recent Events

  • 02 Jun 2026 According to the Institute of Cancer Research Media Release, data from this study were presented at the American Society of Clinical Oncology (ASCO) annual meeting.
  • 02 Jun 2026 Results presented in The Institute of Cancer Research Media Release.
  • 20 Sep 2023 Planned End Date changed from 30 Apr 2028 to 30 Jun 2027.

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