Trial Profile

A Phase Ib Study of the Safety, Pharmacokinetic of APG-2575 Single Agent and in Combination With Homoharringtonine or Azacitidine in Patients With Relapsed/Refractory AML

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 14 Feb 2025

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At a glance

Drugs Azacitidine (Primary) ; Azacitidine (Primary) ; Lisaftoclax (Primary) ; Omacetaxine mepesuccinate (Primary)
Indications Acute biphenotypic leukaemia; Acute myeloid leukaemia; Blastic plasmacytoid dendritic cell neoplasm; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes; Myeloid leukaemia
Focus Adverse reactions
Sponsors Ascentage Pharma

Most Recent Events

06 Nov 2024 According to an Ascentage Pharma media release, the results form this trial will be presented at the 66th ASH Annual Meeting that swill take place on December 7-10, 2024.
06 Nov 2024 Results presented in the Ascentage Pharma Media Release.
14 Oct 2024 Planned End Date changed from 1 Aug 2025 to 1 Aug 2026.

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