Trial Profile

NAUTIKA1: Multicenter, Phase II, Neoadjuvant and Adjuvant Study of Multiple Therapies in Biomarker-Selected Patients With Resectable Stages IB-III Non-Small Cell Lung Cancer

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 13 Aug 2025

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At a glance

Drugs Alectinib (Primary) ; Atezolizumab (Primary) ; Cobimetinib (Primary) ; Entrectinib (Primary) ; Pralsetinib (Primary) ; Vemurafenib (Primary) ; Antineoplastics
Indications Non-small cell lung cancer
Focus Adverse reactions; Therapeutic Use
Acronyms NAUTIKA1
Sponsors Genentech

Most Recent Events

29 Apr 2024 Planned number of patients changed from 146 to 125.
21 Mar 2024 Planned number of patients changed from 85 to 146.
13 Mar 2024 Planned primary completion date changed from 7 Mar 2024 to 30 Dec 2025.

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