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A Phase I/IIa Study on Dose-escalation and Extension of Recombinant Humanized Type II CD20 Monoclonal Antibody MIL62 Injection Combined With BTK Inhibitor Orelabrutinib in the Treatment of Recurrent/Refractory CD20+B-cell Lymphoma

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Trial Profile

A Phase I/IIa Study on Dose-escalation and Extension of Recombinant Humanized Type II CD20 Monoclonal Antibody MIL62 Injection Combined With BTK Inhibitor Orelabrutinib in the Treatment of Recurrent/Refractory CD20+B-cell Lymphoma

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 Apr 2023

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At a glance

  • Drugs MIL-62 (Primary) ; Orelabrutinib (Primary)
  • Indications B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors InnoCare Pharma

    • Most Recent Events

    • 01 Apr 2023 Results(n=80) assessing efficacy and safety of Orelabrutinib in patients with refractory or relapsed chronic lymphocytic leukemia small lymphocytic lymphoma published in the American Journal of Hematology
    • 13 Dec 2022 Results (data cut-off on Jul.15,2022) presented at the 64th American Society of Hematology Annual Meeting and Exposition
    • 11 Nov 2022 Status changed from recruiting to active, no longer recruiting.

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