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An Open, Dose-escalation and Expansion Study With a Dual TORC1/2 Inhibitor of ATG-008 Combined With PD-1 Antibody of Toripalimab in Advanced Solid Tumors

Trial Profile

An Open, Dose-escalation and Expansion Study With a Dual TORC1/2 Inhibitor of ATG-008 Combined With PD-1 Antibody of Toripalimab in Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 28 May 2025

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At a glance

  • Drugs Onatasertib (Primary) ; Toripalimab (Primary)
  • Indications Carcinoma; Cervical cancer; Liver cancer; Nasopharyngeal cancer; Ovarian cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TORCH-2

Most Recent Events

  • 23 May 2025 According to an Antengene Corporation media release, data from this study will be presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place from May 30th to June 3rd in Chicago, IL, the United States.
  • 04 Jun 2024 Results (As of Oct 20, 2023, n=31) assessing safety and efficacy of onatasertib combined with toripalimab in patients with advanced solid tumors presented at the 60th Annual Meeting of the American Society of Clinical Oncology
  • 24 May 2024 Results presented in an Antengene Corporation Media Release.

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