A 6-Week Prospective, Open label, Randomized, in Multicenter Study of, Oseltamivir 300mg per day plus Hydroxychloroquine 800 mg per day versus Combination of Lopipinavir 800mg (or 10 mg/kg ) per day and Ritonavir 200 mg ( or 2.5 mg/kg ) per day plus Oseltamivir 300 mg ( or 4-6 mg /kg ) per day versus Combination of Darunavir 400 mg every 8 hours plus ritonavir 200 mg (or 2.5 mg/kg ) per day plus Oseltamivir 300mg ( or 4-6 mg /kg ) per day plus Hydroxychloroquine 400 mg per day in mild COVID 19 and Combination of Lopipinavir 800 mg (or 10 mg/kg ) per day and Ritonavir 200 mg ( or 2.5 mg/kg ) per day plus Oseltamivir 300 mg ( or 4-6 mg /kg ) per day versus Favipiravir 2400 mg, 2400 mg, and 1200 mg every 8 h on day 1, and a maintenance dose of 1200 mg twice a day plus Lopipinavir 800 mg ( or 10 mg/kg ) per day and Ritonavir 200 mg ( or 2.5 mg/kg ) per day versus Combination of Darunavir 400 mg every 8 hours plus ritonavir 200 mg (or 2.5 mg/kg ) plus Oseltamivir 300 mg (or 4-6 mg /kg ) per day plus Hydroxychloroquine 400 mg per day versus Favipiravir 2400 mg, 2400 mg, and 1200 mg every 8 h on day 1, and a maintenance dose of 1200 mg twice a day plus Darunavir 400 mg every 8 hours Ritonavir 200 mg ( or 2.5 mg/kg ) per day plus Hydroxychloroquine 400 mg per day in moderate to critically illness in COVID 19

Number of patient with Death

description: Any death after treatment adjusted by initial severity in each arm time_frame: Up to 24 weeks

Number of patient with Recovery adjusted by initial severity in each arm

description: Normal pulmonary function, normal O2 saturation after treatment Adjusted by initial severity in each arm time_frame: Up to 24 weeks

Number of day With ventilator dependent adjusted by initial severity in each arm

description: Number of day with ventilator assistant time_frame: Up to 24 weeks

Number of patient developed Acute Respiratory Distress Syndrome After treatment

description: Number of patient developed new ARDS time_frame: Up to 24 weeks

Number of patient with Acute Respiratory Distress Syndrome Recovery

description: Acute Respiratory Distress Syndrome Recovery rate time_frame: Up to 24 weeks

Time to recovery

description: The time to recovery was defined as the time between the first day of antiviral treatment or hospitalization to the day when there was no further requirement for antiviral medication or on-going medical care or the day of discharge from the hospital. time_frame: Up to 24 Weeks ^[1]