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A Phase I Study of Vorinostat in Combination With Vincristine, Irinotecan, and Temozolomide in Children, Adolescents, and Young Adults With Relapsed or Refractory Solid Tumors and CNS Malignancies

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Trial Profile

A Phase I Study of Vorinostat in Combination With Vincristine, Irinotecan, and Temozolomide in Children, Adolescents, and Young Adults With Relapsed or Refractory Solid Tumors and CNS Malignancies

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 31 Oct 2022

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At a glance

  • Drugs Irinotecan (Primary) ; Temozolomide (Primary) ; Vincristine (Primary) ; Vorinostat (Primary) ; Cefixime
  • Indications CNS cancer; Solid tumours
  • Focus Adverse reactions

    • Most Recent Events

    • 24 Oct 2022 Planned End Date changed from 17 Dec 2022 to 31 Dec 2024.
    • 24 Oct 2022 Planned primary completion date changed from 17 Dec 2021 to 31 Dec 2023.
    • 19 Mar 2020 New trial record

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