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A Phase 1 Open-Label, Dose-Ranging Trial to Determine the Safety and Immunogenicity of an Adenoviral-Vector Based Vaccine (VXA-CoV2-1) Expressing a SARS-CoV-2 Antigen and dsRNA Adjuvant Administered Orally to Healthy Adult Volunteers VXA-CoV2-1.1-S Boost Substudy: Boost at 1 Year Post Initial Vaccination With an Adenoviral-Vector Based Vaccine VXA-CoV2-1.1-S Expressing a SARS-CoV-2 S Protein in a Subset of Subjects

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Trial Profile

A Phase 1 Open-Label, Dose-Ranging Trial to Determine the Safety and Immunogenicity of an Adenoviral-Vector Based Vaccine (VXA-CoV2-1) Expressing a SARS-CoV-2 Antigen and dsRNA Adjuvant Administered Orally to Healthy Adult Volunteers VXA-CoV2-1.1-S Boost Substudy: Boost at 1 Year Post Initial Vaccination With an Adenoviral-Vector Based Vaccine VXA-CoV2-1.1-S Expressing a SARS-CoV-2 S Protein in a Subset of Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 24 Jun 2024

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At a glance

  • Drugs VXA CoV2-1 (Primary)
  • Indications COVID 2019 infections
  • Focus Adverse reactions
  • Sponsors Vaxart

    • Most Recent Events

    • 20 Jul 2022 Results published in the Media Release, according to a Vaxart media release.
    • 20 Jul 2022 According to a Vaxart media release, the company intends to publish the complete data from the study in a peer-reviewed journal.
    • 20 Jul 2022 According to a Vaxart media release, additional phase 1 clinical data from this trial published on medRixv.org.

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