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Phase I, Open Label, Study of B-cell Maturation Antigen (BCMA)-Directed CAR-T Cells in Adult Patients With Multiple Myeloma

Trial Profile

Phase I, Open Label, Study of B-cell Maturation Antigen (BCMA)-Directed CAR-T Cells in Adult Patients With Multiple Myeloma

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 27 May 2025

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At a glance

  • Drugs PHE 885 (Primary) ; Bendamustine; Cyclophosphamide; Fludarabine
  • Indications Multiple myeloma
  • Focus Adverse reactions; First in man
  • Sponsors Novartis Pharmaceuticals

Most Recent Events

  • 20 May 2025 Status changed from active, no longer recruiting to discontinued.
  • 10 Dec 2024 Results of Prolonged Persistence and Functional Activity of Anti-BCMA CAR-T Durcabtagene Autoleucel (PHE885) Manufactured Using the T-Charge platform, presented at the 66th American Society of Hematology Annual Meeting and Exposition
  • 24 Jan 2024 Status changed from recruiting to active, no longer recruiting.

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