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A Phase 2a Open-Label, Multi-Center Study to Evaluate the Safety and Tolerability of Multiple Doses of AT-1501 in Adults With ALS

Trial Profile

A Phase 2a Open-Label, Multi-Center Study to Evaluate the Safety and Tolerability of Multiple Doses of AT-1501 in Adults With ALS

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 18 Nov 2024

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At a glance

  • Drugs Tegoprubart (Primary)
  • Indications Amyotrophic lateral sclerosis
  • Focus Adverse reactions; Biomarker
  • Sponsors Anelixis Therapeutics; Eledon Pharmaceuticals

Most Recent Events

  • 01 Oct 2024 Results assessing the safety, tolerability, and impact on pro-inflammatory biomarker profiles of an anti CD40L antibody, tegoprubart, in individuals with amyotrophic lateral sclerosis, published in the PLOS Medicine.
  • 14 Nov 2022 According to an Eledon Pharmaceuticals media release, data from this study were presented at the ALS One 5th Annual ALS Research Symposium and the Northeast Amyotrophic Lateral Sclerosis Consortium (NEALS).
  • 13 Jul 2022 Status changed from active, no longer recruiting to completed.

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