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A Randomized, Double-blind, Placebo-controlled Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Who Are Eligible for Septal Reduction Therapy

Trial Profile

A Randomized, Double-blind, Placebo-controlled Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Who Are Eligible for Septal Reduction Therapy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 22 Nov 2024

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At a glance

  • Drugs Mavacamten (Primary)
  • Indications Hypertrophic cardiomyopathy
  • Focus Registrational; Therapeutic Use
  • Acronyms VALOR-HCM
  • Sponsors Bristol-Myers Squibb

Most Recent Events

  • 11 Nov 2024 According to a Bristol Myers Squibb media release, data from this study will be presented as an Oral Featured Science Presentation on Monday, Nov. 18, 9:57 AM - 10:05 AM, at the American Heart Association (AHA) Annual Scientific Sessions, taking place November 16-18, 2024, in Chicago, Illinois.
  • 02 Sep 2024 Results assessing serial changes in LA strain measures in patients enrolled in the VALOR-HCM trial, presented at the ESC Congress 2024 - Annual Congress of the European Society of Cardiology.
  • 02 Sep 2024 Results assessing effects of mavacamten on heart function in patients with hypertrophic cardiomyopathy (HCM) were published at the ESC Congress 2024 - Annual Congress of the European Society of Cardiology.

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