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A Phase 2/3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Mavrilimumab (KPL-301) Treatment in Adult Subjects Hospitalized With Severe COVID-19 Pneumonia and Hyper-inflammation

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Trial Profile

A Phase 2/3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Mavrilimumab (KPL-301) Treatment in Adult Subjects Hospitalized With Severe COVID-19 Pneumonia and Hyper-inflammation

Status: Completed
Phase of Trial: Phase II/III

Latest Information Update: 24 Jan 2025

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At a glance

  • Drugs Mavrilimumab (Primary)
  • Indications COVID-19 pneumonia; Inflammation
  • Focus Registrational; Therapeutic Use
  • Sponsors Kiniksa Pharmaceuticals

Most Recent Events

  • 22 Jan 2025 primary endpoints has been amended
  • 16 Mar 2022 Status changed from active, no longer recruiting to completed.
  • 28 Dec 2021 Phase 3 portion results presented in a Kiniksa Pharmaceuticals media release.

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