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Palbociclib, Trastuzumab, Pyrotinib and Fulvestrant Treatment in Patients With Brain Metastasis From ER/PR Positive, HER-2 Positive Breast Cancer: A Multi-center, Prospective Study in China

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Trial Profile

Palbociclib, Trastuzumab, Pyrotinib and Fulvestrant Treatment in Patients With Brain Metastasis From ER/PR Positive, HER-2 Positive Breast Cancer: A Multi-center, Prospective Study in China

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 08 Jul 2023

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At a glance

  • Drugs Fulvestrant (Primary) ; Palbociclib (Primary) ; Pyrotinib (Primary) ; Trastuzumab (Primary)
  • Indications Advanced breast cancer; Brain metastases; HER2 positive breast cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 06 Jun 2023 Interim results (Dec 4 202 To Nov 2 2022, n=15) presented at the 59th Annual Meeting of the American Society of Clinical Oncology.
    • 24 Apr 2022 Planned number of patients changed from 48 to 34.
    • 24 Apr 2022 Treatments section has been updated to replace Lapatinib by Pyrotinib.

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