Trial Profile

Phase II Randomized Study of Maintenance Atezolizumab Versus Atezolizumab in Combination With Talazoparib in Patients With SLFN11 Positive Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 11 Apr 2025

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At a glance

06 Jul 2023 Primary endpoint (Progression free survival) has been met according to result presented at the 59th Annual Meeting of the American Society of Clinical Oncology.
06 Jun 2023 Results assessing whether the addition of PARPi (talazoparib) to standard-of-care maintenance ICI (atezolizumab) following frontline chemoimmunotherapy improved outcomes in pts with SLFN11-positive ES-SCLCpresented at the 59th Annual Meeting of the American Society of Clinical Oncology
28 Sep 2022 Status changed from recruiting to active, no longer recruiting.

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