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A Phase 3 Study of Pembrolizumab (MK-3475) in Combination With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib vs Concurrent Chemoradiation Therapy Followed by Durvalumab in Participants With Unresectable, Locally Advanced, Stage III Non-Small Cell Lung Cancer (NSCLC)

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A Phase 3 Study of Pembrolizumab (MK-3475) in Combination With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib vs Concurrent Chemoradiation Therapy Followed by Durvalumab in Participants With Unresectable, Locally Advanced, Stage III Non-Small Cell Lung Cancer (NSCLC)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 11 Jul 2024

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At a glance

  • Drugs Olaparib (Primary) ; Pembrolizumab (Primary) ; Carboplatin; Cisplatin; Durvalumab; Etoposide; Paclitaxel; Pemetrexed
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms KEYLYNK012; MK-7339-012/KEYLYNK-012
  • Sponsors Merck Sharp & Dohme Corp.

    • Most Recent Events

    • 17 Dec 2023 Status changed from recruiting to active, no longer recruiting.
    • 30 Nov 2023 Planned End Date changed from 6 Jul 2026 to 15 Feb 2027.
    • 16 Dec 2021 New source identified and integrated (Japan Pharmaceutical Information Center - Clinical Trials Information record: JapicCTI205352).

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