Phase 1/2 Study of the Safety, Pharmacokinetics, and Preliminary Clinical Activity of BT7480 in Patients With Nectin-4 Associated Advanced Malignancies
Latest Information Update: 25 Nov 2025
At a glance
- Drugs BT 7480 (Primary) ; Nivolumab (Primary)
- Indications Advanced breast cancer; Anal cancer; Carcinoma; Cervical cancer; Gastric cancer; Head and neck cancer; Male breast cancer; Non-small cell lung cancer; Oesophageal cancer; Ovarian cancer; Solid tumours; Squamous cell cancer; Urogenital cancer
- Focus Adverse reactions; First in man; Therapeutic Use
- Sponsors Bicycle Therapeutics
Most Recent Events
- 30 Oct 2025 According to a Bicycle Therapeutics media release, the data from the trial will be presented at the scientific conference in the first half of 2026.
- 04 Feb 2025 Status changed from recruiting to active, no longer recruiting.
- 13 Jan 2025 According to a Bicycle Therapeutics media release, company to report combination data for BT7480 plus nivolumab in 4Q 2025.