UpFrontPSMA : A Randomised Phase 2 Study of Sequential 177Lu-PSMA617 and Docetaxel Versus Docetaxel in Metastatic Hormone-Naive Prostate Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 17 Jan 2025

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At a glance

Drugs Lutetium (177Lu) vipivotide tetraxetan (Primary) ; Dexamethasone; Docetaxel; Ondansetron
Indications Adenocarcinoma; Bone metastases; Prostate cancer
Focus Therapeutic Use
Acronyms UpFrontPSMA

03 Jul 2023 Status changed from recruiting to active, no longer recruiting.
30 Jun 2022 Status changed from suspended to recruiting, according to Novartis media release.
30 Jun 2022 According to Novartis media release, company has remediated the issues that led to the temporary, voluntary suspension. These issues did not affect patient safety, and no risk to patients from the doses previously produced at these sites was identified.Company restarted screening and enrollment for clinical trials with 177Lu-PSMA-617 (lutetium Lu 177 vipivotide tetraxetan) in the US, in most countries globally.

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