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Randomized, double-blind, parallel group, Phase 2b dose-finding, efficacy and safety study of 12-week twice daily oral administration of BAY 1817080 compared to placebo in the treatment of refractory and/or unexplained chronic cough (RUCC)

Trial Profile

Randomized, double-blind, parallel group, Phase 2b dose-finding, efficacy and safety study of 12-week twice daily oral administration of BAY 1817080 compared to placebo in the treatment of refractory and/or unexplained chronic cough (RUCC)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Jul 2023

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At a glance

  • Drugs Eliapixant (Primary)
  • Indications Cough
  • Focus Therapeutic Use
  • Acronyms PAGANINI
  • Sponsors Bayer
  • Most Recent Events

    • 01 Jun 2023 Primary endpoint has been met (Change from baseline in 24-hour cough count (measured by cough recording digital wearable monitoring device) after 12 weeks of intervention) , according to Results published in the Lung.
    • 01 Jun 2023 Results published in the Lung
    • 06 Sep 2021 According to an Evotec SE media release, data were presented during the virtual European Respiratory Society (ERS) International Congress 2021.

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