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Evaluation of the Effects of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer

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Trial Profile

Evaluation of the Effects of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Aug 2025

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At a glance

  • Drugs Abemaciclib (Primary) ; Anastrozole; Fulvestrant; Letrozole
  • Indications Adenocarcinoma; Advanced breast cancer; HER2 negative breast cancer
  • Focus Pharmacodynamics

Most Recent Events

  • 20 Jul 2025 Status changed from active, no longer recruiting to completed.
  • 27 Feb 2025 Planned End Date changed from 30 Dec 2024 to 30 Dec 2025.
  • 27 Feb 2025 Planned primary completion date changed from 30 Dec 2024 to 30 Dec 2025.

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